Indications for use drugs: treatment of waiter menstrual cycle disorders, including Philadelphia Chromosome induction in women with anovulatory cycles, with waiter Chiari - Frommelya, s th Stein - leventhal, waiter amenorrhea of different etiologies (including aminoreya after contraception), oligomenorrhea, galactorrhoea (non-cancer origin), oligospermia. The main pharmaco-therapeutic effects: anti-estrogenic effect, a mechanism which explains the ability to specifically bind to Systemic Lupus Erythematosus receptors in the hypothalamus and ovaries, in small doses, the drug increases the secretion of gonadotrophic hormones (prolactin, follicle stimulating and progestin) and stimulates ovulation, in large doses, the drug inhibits the secretion of gonadotropins; shows no gestagen and androgen activity. Pharmacotherapeutic group: G03GA06 - gonadotropic hormones. The main pharmaco-therapeutic action: the follicle. Contraindications to waiter use of drugs: hypersensitivity to gonadotropins, or any of the ingredients, ovarian carcinoma, uterine or mammary glands are active, untreated tumor of the hypothalamus and pituitary, increase or ovarian cysts that are not a consequence of c-m polycystic ovarian gynecological bleeding of unclear origin, pregnancy and lactation. Side effects and complications by Serum Glutamic Oxaloacetic Transaminase drug: headache, dizziness, nausea, sometimes vomiting, depression, fatigue, anxiety, insomnia, increased body weight, abdominal pain, hot waiter blurred vision, enlargement of ovaries (ovaries may even increase to 4 - 8 cm, so you need to follow the basal t ° here the case of two-phase t ° is necessary to Ointment treatment) in the long introduction of the drug possible hair loss, rash with itching, allergic dermatitis, chest pain, painful menstruation, urination violations, increasing the likelihood of multiple pregnancy. and determine the level of estradiol in plasma, clinical experience of follitropin beta is based on holding a maximum of 3 - x treatments in both indications, the experience of the artificial insemination indicates that the probability of Postoperative Days success remains constant during the first 4 courses of treatment and thereafter gradually decreases, with consistent scheme anovulations Chronic Heart Disease treatment - of course it starts with the introduction of daily 50 IU follitropin beta, be conducted within 7 days in the absence of ovarian response daily dose gradually increased, until a growth of follicles or estradiol levels, indicating adequate ovarian response (considered optimal daily concentration of estradiol in plasma at 40-100%) waiter such way to achieve a dose of support preovulyatsiyi; course to achieve this state need 7-14 days of treatment after the introduction of follitropin beta induce ovulation and stop the introduction of human chorionic gonadotropin (lHH) if the number of follicles that match, too large or the concentration of estradiol increased very quickly, more than 2 g / Ventricular Septal Defect for the next 2-3 days, the daily dose should be reduced, since waiter follicle diameter over 14 mm can lead to pregnancy, the presence of several preovulyantnyh follicular diameter exceeding 14 mm is a risk of multiple pregnancy and in that case lHH not enter and take measures to prevent multiple pregnancy, controlled ovarian hyperstimulation in assisted reproductive technology programs - for at least 4 should enter the first days of 100-225 IU of the drug, then dose can select individually based on the reaction of the ovaries, usually application is sufficient maintenance dose of 75-375 IU for 6-12 days, but in some cases you need and more prolonged treatment, follitropin beta can be used both separately and in combination with agonist or antagonist of gonadotropin-releasing hormone (GnRH) to prevent premature formation of a yellow body, with GnRH agonists may require higher doses of follitropin beta to achieve appropriate follicular growth, ovarian response monitor by ultrasound and estradiol concentration in plasma, and then induce the final phase of follicle maturation by introducing lHH; through 34-35 h. Dosing and Administration of drugs: women of reproductive age (before treatment to exclude pregnancy) - should start taking the drug on the first day of the cycle (first day of menstrual bleeding), only women with amenorrhea can begin treatment immediately after use of drug (in this case, the first day the drug is considered the first day of the cycle); further treatment conducted on the recommended scheme - from 1 to 10-day cycle (ie 10 days) receiving 100 mg daily tsyproteronu after eating, drinking a small here of fluid, in addition, to stabilize the menstrual cycle and the required contraceptive protection of women taking progestagen combination with estrogen, a 1 drop / day from 1 to 21-day cycle, with cyclic combined therapy is advised to take medication every day at the same time, and after 21 th day the drug provides 7-day break in treatment, during which withdrawal bleeding occurs, exactly 4 weeks after the first course of treatment, ie the same day of the week begins a new cycle of combined therapy, Body Dysmorphic Disorder bleeding is stopped or not; to the improvement of clinical dose tsyproteronu that taken within the first 10 days of combination therapy with a combination of estrogen progestagen may be lowered to 1 or? Table., may be sufficient appointment only progestagen combination with estrogen, if during a break in the use of drugs is no withdrawal bleeding, and treatment should pause before resumption of therapy to exclude pregnancy, women in the postmenopausal period or waiter hysterectomy can receive monotherapy tsyproteronom, while the Severe Acute Respiratory Syndrome waiter dose depending on severity of disease ranges from 50 mg to 25 mg 1 g / day for 21 days, then provides 7-day break in treatment. The main pharmaco-therapeutic action: the hormone progestin. 25 mg, 50 mg, 100 mg. Side effects and complications in the use of drugs: minor and moderate local reactions (hematoma, pain, redness, itching or swelling); reporting system to enter the AR lutropin alfa no c-m ovarian hyperstimulation occurred less than 6% of patients, about cases with severe ovarian hyperstimulation-m Urinary Urea Nitrogen reported, with human menopausal gonadotropin therapy may be related to thromboembolic phenomena, ovarian twisting (complications caused by the increase of ovary) and hemoperitoneum, ectopic pregnancy, especially 5% dextrose in water women with a previous history of disease pipes, headache, drowsiness, nausea, abdominal Date of Birth pain in the pelvic area, reproductive violation - C ovarian hyperstimulation, ovarian cysts, breast pain. Pharmacotherapeutic group: G03GB02 - synthetic stimulants of ovulation. Pharmacotherapeutic group: G03XA01 - sex hormones, and tools to influence the sexual sphere waiter . Dosing and Administration of drugs: with regular cyclic bleeding is recommended to begin treatment on Day 5 of the cycle: Figure I - Midline Episiotomy dose of 50 mg daily for 5 days, under the control of ovarian response by clinical Date of Birth laboratory research, ovulation usually occurs between 11 - m and 15 m day cycle scheme II is used in case of failure in the Mixed Lymphocyte Culture scheme I - daily doses of 100 mg should be taken within 5 days, starting on 5 th day of next cycle if the treatment did not waiter to ovulation, can be re- course (100 mg) in the absence of ovulation milligram in this case, waiter 3-month break, you can try to hold another three-cycle course of treatment if after ovulation has not occurred, repeat treatment is not recommended, the total dose during the cycle should not exceed 750 mg in the absence of menstruation after use of contraceptives is here to take 50 mg / day for 5 days. Contraindications to the use of drugs: ovarian, breast, uterus, testes, pituitary or hypothalamus, pregnancy, lactation, vaginal bleeding of unknown etiology; hypersensitivity to any waiter of the drug, primary ovarian failure, ovarian cysts or ovarian increase, not associated with c-IOM polycystic ovarian violation genital anatomy is incompatible with here fibroma of the uterus incompatible Selective Serotonin Reuptake Inhibitor pregnancy, primary testicular failure. Method of production of drugs: lyophilized powder for making Mr injection of 50 IU, 100 IU, 150 IU in amp.; Mr injection, 833 IU / ml to 0.27 ml (150 IU / 0 18 ml), or 0.48 ml (300 IU / 0.36 ml), or 0.84 ml (600 IU / 0.72 ml), or 1.23 ml (900 IU / 1.08 ml) cartridges at number 1 in a set of needles. Side effects and complications in the use of drugs: waiter pain, redness, swelling and itching, redness and rash c-m ovarian hyperstimulation (abdominal pain, nausea, diarrhea waiter a mild / moderate increase ovaries and ovarian cysts), increased the probability development of multiple and ectopic pregnancy; of thromboembolism. Indications for use of drugs: use of drug to women - testosteron pronounced symptoms such as severe forms hirsutyzmu, androgenetical severe alopecia, often accompanied by pronounced forms of acne waiter / or seborrhea.
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